Wow, it's been a long time since I've posted on DW!
I love the Losers! I like both the movie and the comic, so taking from either source would be fine. I am especially fond of fix-its for the ending of the comic.
I like anything about the team, but my favorites are Jensen and Cougar. I definitely ship it. Roque makes me sad, so things set before his betrayal, or things that re-frame it so that it's not a betrayal are also very welcome. Redeemed Roque is my favorite Roque.
I like AU's just fine, but I'm less fond of supernatural ones (they're werewolves, they're shifters, etc). I don't HATE them, they just aren't my favorite. I'm also really over a/b/o - kind of got my fill a few years ago.
Crossovers are OK, but not my favorite. They're better if they're fandoms I'm familiar with - my favorite fandoms are Marvel (MCU or comics), Stargate Atlantis, NCIS, Supernatural. I kind of like crossovers that use other characters that the actors in The Losers have played. In that vein, I'm more familiar with Chris Evans's, Idris Elba's, and Jeffrey Dean Morgan's body of work. (Well, I know Pacific Rim).
Any rating is fine. Pretty open if you want to do explicit, especially explicit slash. I'm more than fine with anything except watersports and scat. Again, a/b/o is not my jam.